Part Ⅰ Technical Development and Challenges in the Surgical Treatment of Hepatocellular Carcinoma Chapter 1 Etiology and Epidemiology of Hepatocellular Carcinoma Chapter 2 Current Status of Surgical Treatment for HCC Chapter 3 Development of Hepatectomy for HCC Section 1 Anatomic Hepatectomy and Non-anatomic Hepatectomy Section 2 Application of ALPPS and PVE Section 3 Laparoscopic Hepatectomy Section 4 Robotic Surgical Systems and Remote Hepatectomy Section 5 Minimally Invasive Liver Resection versus Open Liver Resection: Indications and Outcomes Chapter 4 Application of Artif icial Intelligence and Imaging Technology in Hepatectomy Section 1 Preoperative Assessment and Planning Section 2 Intraoperative Navigation Systems Chapter 5 Extent of Hepatectomy for HCC and Areas of Controversy Section 1 Controversy Between Anatomical Resection and Nonanatomical Resection Section 2 The Importance of R0 Resection and the Controversy Between Wide and Narrow Margins Chapter 6 Strategies and Challenges in Hepatectomy for HCC with Vascular Invasion Section 1 Overview of HCC with Vascular Invasion Section 2 Hepatectomy in Patients with Macrovascular Invasion Section 3 Hepatectomy in Patients with MVI Scientif ic Hepatectomy A New Concept in Surgical Treatment of Hepatocellular Carcinoma Chapter 7 Limitations of Curative Hepatectomy for HCC Section 1 Origins and Independent Risk Factors for Postoperative Recurrence Section 2 Clinical Challenges and Countermeasures Chapter 8 Regional Differences in Indications for Hepatectomy and Liver Transplantation for HCC Section 1 China Section 2 Other Asian Countries Section 3 Europe and North America Section 4 African Countries Chapter 9 Advances and Challenges in Liver Transplantation for HCC Section 1 Development and Current Status Section 2 Dilemmas and Challenges Part Ⅱ Concepts and Practice of Scientif ic Hepatectomy for HCC in the Era of Immunotherapy Chapter 10 Mechanisms of Immune Evasion and Advances in Immunotherapy for HCC Section 1 Mechanisms of Immune Evasion in HCC Section 2 Advances in Immunotherapy for HCC Chapter 11 Systemic Stress Response and Immunotherapy After Hepatectomy for HCC Section 1 Postoperative Stress State and Changes in Immune Function After Hepatectomy for HCC Section 2 Impact of Hepatectomy—Induced Surgical Stress on the Eff icacy of Immunotherapy for HCC Chapter 12 The Concept of Scientif ic Hepatectomy for HCC Chapter 13 Cirrhosis Grading and the Safety and Eff icacy of Hepatectomy Section 1 Cirrhosis Grading and the Safety of Hepatectomy Section 2 Cirrhosis Grading and the Eff icacy of Hepatectomy Chapter 14 A Preoperative Safety Assessment System for Hepatectomy in HCC Chapter 15 Conversion Strategies for Unresectable HCC Section 1 Conversion Treatment for Large and Huge HCC Section 2 Conversion Treatment for Intermediate- and Advanced- Stage Unresectable HCC Section 3 The Role of Local Therapy in C Section 1 Treatment Strategies for Resectable HCC with Hypersplenism Section 2 Treatment Strategies for Unresectable HCC with Hypersplenism Part Ⅲ Typical Cases in the Practice of Scientif ic Hepatectomy Chapter 19 Long?Term Survival in HCC After Conversion and Neoadjuvant Therapy Case 1 Targeted Therapy and Immunotherapy Combined with Local Therapy Enabled Conversion Resection and Long-Term Survival in Advanced Giant Hepatocellular Carcinoma Case 2 Insuff icient Future Liver Remnant Achieving Cure After Down?sized Tumor Followed by Limited Hepatectomy Following Conversion Therapy Case 3 Hepatocellular Carcinoma with Portal Vein Tumor Thrombus Achieves Stable Disease after Combined Targeted and Immunotherapy Followed by Microwave Ablation Scientif ic Hepatectomy A New Concept in Surgical Treatment of Hepatocellular Carcinoma Tumor-free Margins Case 5 Complete Response of Unresectable Advanced Giant Hepatocellular Carcinoma After HAIC Combined with Targeted Therapy and Immunotherapy Case 6 Long-Term Complete Remission of Unresectable HCC After TACE Combined with Targeted Therapy and Immunotherapy Case 7 Complete Tumor Remission of Multifocal HCC After TACE Combined with Targeted Therapy and Immunotherapy Case 8 Complete Response Achieved with TACE Combined with Targeted Therapy Plus Immunotherapy in a Patient with Hepatocellular Carcinoma Who Refused Surgical Resection Case 9 Hepatocellular Carcinoma with Vascular Invasion Achieving Complete Response After TACE Combined with Targeted Therapy and Immunotherapy Case 10 Hepatocellular Carcinoma Unsuitable for Hepatic Resection Treated with TACE Combined with Anti-PD-1 Immunotherapy and Targeted Therapy Chapter 20 Long?Term Survival in Recurrent HCC After Hepatectomy Treated with Combination Immunotherapy Case 1 Complete Response Achieved with Targeted-Immunotherapy Combination in a Patient with HCC Complicated by Liver Cirrhosis and MVI Following Resection and Subsequent Recurrence/Metastasis Case 2 Recurrence of Hepatocellular Carcinoma with Portal Vein Invasion After Hepatectomy, Achieving Cure with Targeted Therapy and Immunotherapy Case 3 Recurrence of Multifocal Hepatocellular Carcinoma After Hepatectomy, Achieving Complete Response with TACE Plus Targeted Therapy and Immunotherapy Case 4 Complete Response Achieved with the STRIDE Regimen Following HCC Recurrence After Resection and Adjuvant Therapy for Ruptured HCC Chapter 21 Cases of Long?Term Survival Achieved by Palliative Hepatectomy Combined with Immunotherapy for Advanced Hepatocellular Carcinoma Case 1 Curative Outcome in a Patient with Advanced HCC and Lung Metastases Treated with Palliative Hepatectomy Followed by Autologous Tumor-Inf iltrating Lymphocyte Infusion and Anti-PD-1 Therapy Case 2 Curative Outcome in a Patient with Advanced HCC Treated with Autologous Tumor-Inf iltrating Lymphocyte Infusion and Anti-PD-1 Therapy After Palliative Hepatectomy
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