本書基於美國經典版教材《遺傳學》Essentials of Genetics（第10版）改編而來，作者結合中國遺傳學教學總體情況及個人十多年的教學經驗對原版教材進行了翻譯和改編，並補充了網路版學習指導材料及習題，更貼合中國學生的學習情況。本書不僅適合作為生物學相關專業本科生的基礎教材，也可作為研究生或科研人員的重要參考用書。
1 Introduction to Genetics 1 緒論 1.1 Genetics Has an Interesting Early History 1.1 有趣的遺傳學早期歷史 1.2 Genetics Progressed from Mendel to DNA in Less Than a Century 1.2 從孟德爾到DNA——遺傳學在一個世紀內的飛速進展 1.3 Discovery of the Double Helix Launched the Era of Molecular Genetics 1.3 DNA雙螺旋結構的發現開啟了分子遺傳學新紀元 1.4 Development of Recombinant DNA Technology Began the Era of DNA Cloning 1.4 重組DNA技術的發展開啟了DNA克隆時代 1.5 The Impact of Biotechnology Is Continually Expanding 1.5 生物技術的影響正持續擴大 1.6 Genomics, Proteomics, and Bioinformatics Are New and Expanding Fields 1.6 基因組學、蛋白質組學和生物信息學是日益發展的新興領域 1.7 Genetic Studies Rely on the Use of Model Organisms 1.7 遺傳學研究依賴於模式生物的使用 1.8 Genetics Has Had a Profound Impact on Society 1.8 遺傳學對社會已經產生了深遠影響 2 Mitosis and Meiosis 2 有絲分裂和減數分裂 2.1 Cell Structure Is Closely Tied to Genetic Function 2.1 細胞結構與遺傳功能緊密相關 2.2 Chromosomes Exist in Homologous Pairs in Diploid Organisms 2.2 二倍體生物中染色體以同源染色體對的形式存在 2.3 Mitosis Partitions Chromosomes into Dividing Cells 2.3 有絲分裂將染色體分配至分裂細胞中 2.4 Meiosis Creates Haploid Gametes and Spores and Enhances Genetic Variation in Species 2.4 減數分裂產生單倍體配子和孢子並增加了物種的遺傳變異 2.5 The Development of Gametes Varies in Spermatogenesis Compared to Oogenesis 2.5 精子發生與卵子發生中的配子發育差異 2.6 Meiosis Is Critical to Sexual Reproduction in All Diploid Organisms 2.6 減數分裂對於所有二倍體生物的有性生殖都至關重要 2.7 Electron Microscopy Has Revealed the Physical Structure of Mitotic and Meiotic Chromosomes 2.7 電子顯微鏡揭示了有絲分裂和減數分裂過程中的染色體結構 3 Mendelian Genetics 3 孟德爾遺傳學 3.1 Mendel Used a Model Experimental Approach to Study Patterns of Inheritance 3.1 孟德爾使用模型實驗方法研究遺傳模式 3.2 The Monohybrid Cross Reveals How One Trait Is Transmitted from Generation to Generation 3.2 單因子雜交揭示了單一性狀世代傳遞的規律 3.3 Mendel』s Dihybrid Cross Generated a Unique F2 Ratio 3.3 孟德爾雙因子雜交產生獨特的F2 代比例 3.4 The Trihybrid Cross Demonstrates That Mendel』s Principles Apply to Inheritance of Multiple Traits 3.4 三因子雜交表明孟德爾定律適用於多性狀遺傳 3.5 Mendel』s Work Was Rediscovered in the Early Twentieth Century 3.5 孟德爾的工作在20 世紀初被重新發現 3.6 Independent Assortment Leads to Extensive Genetic Variation 3.6 自由組合產生廣泛的遺傳變異 …… 4 Modification of Mendelian Ratios
4 孟德爾比率的擴展 5 Sex Determination and Sex Chromosomes 5 性別決定與性染色體 6 Chromosome Mutations: Variation in Number and Arrangement 6 染色體突變: 染色體數目與結構的變異 7 Linkage and Chromosome Mapping in Eukaryotes 7 真核生物的連鎖與染色體作圖 8 Genetic Analysis and Mapping in Bacteria and Bacteriophages 8 細菌和噬菌體的遺傳分析與染色體作圖 9 Epigenetics 9 表觀遺傳學 10 Genetic Testing 10 遺傳檢測 11 Gene Therapy 11 基因治療 12 Advances in Neurogenetics: The Study of Huntington Disease 12 神經遺傳學進展：亨廷頓病的研究 13 DNA Forensics 13 DNA 法醫學 14 Genetically Modified Foods 14 轉基因食品 15 Genomics and Precision Medicine 15 基因組學與精準醫療
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