Chapter 1 Introduction 1.1 Brief history of clinical epidemiology 1.2 Definition of clinical epidemiology 1.3 Roles of clinical epidemiology 1.4 Methodology of clinical epidemiologic study 1.5 Characteristics of clinical epidemiology Chapter 2 Distribution of Disease 2.1 Measures of disease frequency 2.2 Epidemic disease occurrence 2.3 Distribution of disease by time,place and person Chapter 3 Descriptive Study 3.1 Introduction 3.2 Case and case series report 3.3 Cross-sectional study 3.4 Ecological study Chapter 4 Cohort Study 4.1 Introduction 4.2 Design of a cohort study 4.3 Data collection and analysis 4.4 Common bias and controlling 4.5 Advantages and disadvantages of cohort studies 4.6 Example of a cohort study Chapter 5 Case-Control Studies 5.1 Overview of case-control studies 5.2 Design of case-control studies 5.3 Data collection and analysis 5.4 Common bias and controlling 5.5 Advantage and disadvantage of the case-control study Chapter 6 Experimental Epidemiology 6.1 Basic ideas of experimental study 6.2 Clinical trial 6.3 Field trial 6.4 Community trial Chapter 7 Screening and Diagnostic Tests 7.1 Design a screening or diagnostic test 7.2 Evaluation of a screening test 7.3 Improving the efficiency of screening and diagnostic tests 7.4 Potential bias in screening tests Chapter 8 Bias and Interaction 8.1 Introduction of bias 8.2 Selection bias 8.3 Information bias 8.4 Confounding bias Chapter 9 Cause of Disease and Causal Inferen'ce 9.1 Introduction 9.2 Cause of disease in epidemiology 9.3 Epidemiologic methods of causation 9.4 Causal inference Chapter 10 Disease prevention and surveillance 10. 1 Prevention strategies and measures
10.2 Public health monitoring Chapter 11 Communicable Diseases Epidemiology 11.1 Infection process 11.2 Epidemic process 11.3 Strategy and implementation 11.4 Immunization program and effectiveness 11.5 Emerging communicable diseases Chapter 12 Epidemiology of Non-communicable Disease 12.1 Introduction 12.2 Epidemiological features 12.3 Risk factors of several common NCDs 12.4 Prevention and control of NCDs Chapter 13 Epidemiology of Public Health Emergencies 13.1 Basic conception of public health emergencies 13.2 Basic principles and application of epidemiology in public health emergencies 13.3 Public health emergency preparedness 13.4 Public health emergency response Chapter 14 Molecular Epidemiology 14.1 Introduction 14.2 Classes of biomarkers 14.3 Main research methods used in molecular epidemiology 14.4 Application and prospection Chapter 15 Pharmacoepidemiology 15.1 A brief history and definition 15.2 Main research contents 15.3 Aims and significances 15.4 Methods of pharmacoepidemiology 15.5 Data collection and analyze Chapter 16 Evidence-based Medicine and Systematic Review 16.1 Evidence-based medicine 16.2 Systematic review and meta-analysis 16.3 Meta-analysis Chapter 17 Disease Prognosis 17.1 Basic concepts 17.2 Design of a prognosis study 17.3 Describing prognosis 17.4 Analysis for prognosis study data 17.5 Common bias and controlling Chapter 18 Nosocomial Infections 18.1 Introduction 18.2 Definition and diagnostic standards 18.3 Nosocomial infection sites 18.4 Microorganisms 18.5 Categories of nosocomial infections 18.6 Epidemic process of nosocomial infection 18.7 Prevention of nosocomial infections 18.8 Surveillance of nosocomial infections Chapter 19 Epidemiology Design in Clinical Research 19.1 Design and implementation of clinical research 19.2 Reporting guidelines for clinical research reports