目錄
Chapter 1 Introduction of Laboratory Animal Science
1.1 History of Laboratory Animal Science
1.2 Organizations Associated with Laboratory Animal Science
1.3 Animal Welfare
1.4 Animals Used in Research, Product Safety Testing and Teaching
1.5 Regulations, Policies and Principles Governing the Care and Use of Laboratory Animals
1.6 Facility, Equipment, Housing and Management
1.7 Classifications of Animals According to the Burden of Resident Micro-organisms
Chapter 2 Mice
2.1 Genetics
2.2 Ecological Types
2.3 Uses
2.4 Behavior
2.5 Anatomic and Physiologic Features
2.6 Breeding and Reproduction
2.7 Housing and Environment
2.8 Environmental Enrichment
2.9 Feeding and Watering
2.10 Sanitation
2.11 Techniques
Chapter 3 Rats
3.1 Genetics
3.2 Ecologic Types
3.3 Uses
3.4 Behavior
3.5 Anatomic and Physiologic Features
3.6 Breeding and Reproduction
3.7 Housing and Environment
3.8 Environmental Enrichment
3.9 Feeding and Watering
3.10 Sanitation
3. 11 Techniques
Chapter 4 Gerbils
4.1 Uses
4.2 Behavior
4.3 Anatomic and Physiologic Features
4.4 Breeding and Reproduction
4.5 Housing and Environment
4.6 Sanitation
4.7 Environmental Enrichment
4.8 Feeding and Watering
4.9 Techniques
Chapter 5 Hamsters
5.1 Uses
5.2 Behavior
5.3 Anatomic and Physiologic Features
5.4 Breeding and Reproduction
5.5 Housing and Environment
5.6 Sanitation
5.7 Environmental Enrichment
5.8 Feeding and Watering
5.9 Techniques
Chapter 6 Guinea Pigs
6.1 Uses
6.2 Behavior
6.3 Anatomic and Physiologic Features
6.4 Breeding and Reproduction
6.5 Housing and Environment
6.6 Sanitation
6.7 Environmental Enrichment
6.8 Feeding and Watering
6.9 Techniques
Chapter 7 Rabbits
7.1 Breeds
7.2 Uses
7.3 Behavior
7.4 Anatomic and Physiologic Features
7.5 Breeding and Reproduction
7.6 Housing and Environment
7.7 Environmental Enrichment
7.8 Feeding and Watering
7.9 Sanitation
7.10 Techniques
Chapter 8 Cats
8.1 Uses
8.2 Behavior
8.3 Anatomic and Physiologic Features
8.4 Breeding and Reproduction
8.5 Handling and Restraint
8.6 Identification Methods
8.7 Signs of Pain, Distress or Illness
8.8 Housing and Environment
8.9 Environmental Enrichment
8.10 Euthanasia
Chapter 9 Dogs
9.1 Uses
9.2 Behavior
9.3 Anatomic and Physiologic Features
9.4 Breeding and Reproduction
9.5 Handling and Restraint
9.6 Identification Methods
9 7 Signs of Pain. Distress or Illness
9.8 Housing and Environment
9.9 Environmental Enrichment
9.10 Euthanasia
Chapter 10 Pigs
10.1 Uses
10.2 Behavior
10.3 Anatomic and Physiologic Features
10.4 Breeding and Reproduction
10.5 Handling and Restraint
10.6 Identification Methods
10.7 Signs of Pain, Distress or Illness
10.8 Housing and Environment
10.9 Environmental Enrichment
10.10 Euthanasia
Chapter 11 Nonhuman Primates
11.1 Strepsirrhini (Prosimians)
11.2 Haplorrhini (Tarsiers, Monkeys and Apes, Including Humans)
11.3 Uses
11.4 Behavior
11.5 Anatomic and Physiologic Features
11.6 Breeding and Reproduction
11.7 Housing and Environment
11.8 Environmental Enrichment
11.9 Feeding and Watering
11.10 Sanitation
11.11 Techniques
Chapter 12 Amphibians
12.1 Anatomic and Physiologic Features
12.2 Handling and Restraint
12.3 Identification Methods
12.4 Behavior
12.5 Signs of Pain, Distress or Illness
12.6 Husbandry and Diet
12.7 Environmental Enrichment
12.8 Euthanasia
Chapter 13 Animal Genetics and Breeding
13.1 Dominant and Recessive Alleles
13.2 Gene Symbols
13.3 Genotype and Pbenotype
13.4 Homozygotes and Heterozygotes
13.5 Gene Expression
13.6 Gene Linkage
13.7 Strain and Stock Nomenclature
13.8 Breeding and Reproduction
13.9 Mating Systems
13.10 Breeding Schemes
13.11 Genetic Engineering
13.12 Gene-Targeted Mutations
13.13 Applications of Transgenic Animals
Chapter 14 Laboratory Techniques
14.1 Injection 'Feehniques
14.2 Blood Collection Techniques
14.3 Other Techniques
Chapter 15 Research Methodology
15.1 Acute Toxicity Tests
15,2 Subchronic Toxicity Tests
15.3 Chronic Tests
15.4 Reproductive Tests
15.5 Micronucleus Tests
15.6 PyrogenTests
15.7 Induced Cancer Models
15.8 Spontaneous Cancer Models
Appendix
Appendix 1 The U.S. Government Principles for the Utilization and Care of
Vertebrate Animals Used in Testing, Research and Training
Appendix 2 Example of Animal Use Protocol
Appendix 3 Normal Values
Appendix 4 Frequently Asked Questions in Animal Research
Appendix 5 Useful Web Sites for Laboratory Animal Science
References
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